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Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma

Genetic, biochemical, and animal model studies strongly suggest a central role for α-synuclein in the pathogenesis of Parkinson's disease. α-synuclein lacks a signal peptide sequence and has thus been considered a cytosolic protein. Recent data has suggested that the protein may be released fro...

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Detalles Bibliográficos
Autores principales: Emmanouilidou, Evangelia, Elenis, Dimitris, Papasilekas, Themis, Stranjalis, Georgios, Gerozissis, Kyriaki, Ioannou, Penelopi C., Vekrellis, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136497/
https://www.ncbi.nlm.nih.gov/pubmed/21779395
http://dx.doi.org/10.1371/journal.pone.0022225