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Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
Genetic, biochemical, and animal model studies strongly suggest a central role for α-synuclein in the pathogenesis of Parkinson's disease. α-synuclein lacks a signal peptide sequence and has thus been considered a cytosolic protein. Recent data has suggested that the protein may be released fro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136497/ https://www.ncbi.nlm.nih.gov/pubmed/21779395 http://dx.doi.org/10.1371/journal.pone.0022225 |