Subdominant/Cryptic CD8 T Cell Epitopes Contribute to Resistance against Experimental Infection with a Human Protozoan Parasite

During adaptive immune response, pathogen-specific CD8(+) T cells recognize preferentially a small number of epitopes, a phenomenon known as immunodominance. Its biological implications during natural or vaccine-induced immune responses are still unclear. Earlier, we have shown that during experimen...

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Detalles Bibliográficos
Autores principales: Dominguez, Mariana R., Silveira, Eduardo L. V., de Vasconcelos, José Ronnie C., de Alencar, Bruna C. G., Machado, Alexandre V., Bruna-Romero, Oscar, Gazzinelli, Ricardo T., Rodrigues, Mauricio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136500/
https://www.ncbi.nlm.nih.gov/pubmed/21779365
http://dx.doi.org/10.1371/journal.pone.0022011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136500/
https://www.ncbi.nlm.nih.gov/pubmed/21779365
http://dx.doi.org/10.1371/journal.pone.0022011

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