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Reduced cAMP, Akt Activation and p65-c-Rel Dimerization: Mechanisms Involved in the Protective Effects of mGluR3 Agonists in Cultured Astrocytes

In recent decades, astrocytes have emerged as key pieces in the maintenance of normal functioning of the central nervous system. Any impairment in astroglial function can ultimately lead to generalized disturbance in the brain, thus pharmacological targets associated with prevention of astrocyte dea...

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Detalles Bibliográficos
Autores principales: Durand, Daniela, Carniglia, Lila, Caruso, Carla, Lasaga, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136520/
https://www.ncbi.nlm.nih.gov/pubmed/21779400
http://dx.doi.org/10.1371/journal.pone.0022235