Inhibition of Reactive Gliosis Prevents Neovascular Growth in the Mouse Model of Oxygen-Induced Retinopathy

Retinal neovascularization (NV) is a major cause of blindness in ischemic retinopathies. Previous investigations have indicated that ischemia upregulates GFAP and PDGF-B expression. GFAP overexpression is a hallmark of reactive gliosis (RG), which is the major pathophysiological feature of retinal d...

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Detalles Bibliográficos
Autores principales: DeNiro, Michael, Al-Mohanna, Falah H., Al-Mohanna, Futwan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136522/
https://www.ncbi.nlm.nih.gov/pubmed/21779402
http://dx.doi.org/10.1371/journal.pone.0022244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136522/
https://www.ncbi.nlm.nih.gov/pubmed/21779402
http://dx.doi.org/10.1371/journal.pone.0022244

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