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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
FoxO transcription factors play a conserved role in longevity and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans and mice. However, the extent and importance of the...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136551/ https://www.ncbi.nlm.nih.gov/pubmed/21423206 http://dx.doi.org/10.1038/onc.2011.35 |