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The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor
FoxO transcription factors play a conserved role in longevity and act as tissue-specific tumor suppressors in mammals. Several nodes of interaction have been identified between FoxO transcription factors and p53, a major tumor suppressor in humans and mice. However, the extent and importance of the...
Autores principales: | Renault, Valérie M., Thekkat, Pramod U., Hoang, Kimmi L., White, Jamie L., Brady, Colleen A., Broz, Daniela Kenzelmann, Venturelli, Ophelia S., Johnson, Thomas M., Oskoui, Philip R., Xuan, Zhenyu, Santo, Evan E., Zhang, Michael Q., Vogel, Hannes, Attardi, Laura D., Brunet, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136551/ https://www.ncbi.nlm.nih.gov/pubmed/21423206 http://dx.doi.org/10.1038/onc.2011.35 |
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