HEXIM1 is a critical determinant of the response to tamoxifen

Tamoxifen resistance is a major problem in the treatment of Estrogen Receptor (ER) positive patients. We have previously reported that Hexamethylene bis-acetamide Inducible Protein 1 (HEXIM1) inhibits ERα activity by competing with ERα for binding to cyclin T1, a subunit of Positive Transcription El...

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Detalles Bibliográficos
Autores principales: Ketchart, Wannarasmi, Ogba, Ndiya, Kresak, Adam, Albert, Jeffrey M., Pink, John J., Montano, Monica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136650/
https://www.ncbi.nlm.nih.gov/pubmed/21423213
http://dx.doi.org/10.1038/onc.2011.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136650/
https://www.ncbi.nlm.nih.gov/pubmed/21423213
http://dx.doi.org/10.1038/onc.2011.76

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