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Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation

Invasive breast cancer is the major cause of death among females and its incidence is closely linked to HER2 (human epidermal growth factor receptor 2) overexpression. Pterostilbene, a natural analog of resveratrol, exerts its cancer chemopreventive activity similar to resveratrol by inhibiting canc...

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Detalles Bibliográficos
Autores principales: Pan, Min-Hsiung, Lin, Ying-Ting, Lin, Chih-Li, Wei, Chi-Shiang, Ho, Chi-Tang, Chen, Wei-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136680/
https://www.ncbi.nlm.nih.gov/pubmed/19617202
http://dx.doi.org/10.1093/ecam/nep093