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Can Viruses be Modified to Achieve Sustained Gene Transfer
It is very easy to replace a faulty gene in an immunocompromised mouse. First, one takes a well-characterized virus, such as an adenovirus or an adeno-associated virus, and incorporates the correct version of the faulty gene together with some regulatory sequences into the genome. Then, one transduc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136725/ https://www.ncbi.nlm.nih.gov/pubmed/21808636 http://dx.doi.org/10.3389/fmicb.2011.00152 |