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Herbal Medicine Containing Licorice May Be Contraindicated for a Patient with an HSD11B2 Mutation

Licorice ingestion, as well as mutations in the HSD11B2 gene, inhibits 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) enzyme activity, causing the syndrome of apparent mineral corticoid excess (AME). However, the combined effect of licorice ingestion and an HSD11B2 mutation has never been reporte...

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Detalles Bibliográficos
Autores principales: Harahap, Indra Sari Kusuma, Sasaki, Naoko, Gunadi, Yusoff, Surini, Lee, Myeong Jin, Morikawa, Satoru, Nishimura, Noriyuki, Sasaki, Tomohiro, Usuki, Seiichiro, Hirai, Midori, Ohta, Mika, Takaoka, Yutaka, Nishimoto, Takashi, Nishio, Hisahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136776/
https://www.ncbi.nlm.nih.gov/pubmed/20007258
http://dx.doi.org/10.1093/ecam/nep211