IL-1β Promotes TGF-β1 and IL-2 Dependent Foxp3 Expression in Regulatory T Cells

Earlier, we have shown that GM-CSF-exposed CD8α− DCs that express low levels of pro-inflammatory cytokines IL-12 and IL-1β can induce Foxp3+ Tregs leading to suppression of autoimmunity. Here, we examined the differential effects of IL-12 and IL-1β on Foxp3 expression in T cells when activated in th...

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Detalles Bibliográficos
Autores principales: Ganesh, Balaji B., Bhattacharya, Palash, Gopisetty, Anupama, Sheng, Jianrong, Vasu, Chenthamarakshan, Prabhakar, Bellur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136935/
https://www.ncbi.nlm.nih.gov/pubmed/21779356
http://dx.doi.org/10.1371/journal.pone.0021949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136935/
https://www.ncbi.nlm.nih.gov/pubmed/21779356
http://dx.doi.org/10.1371/journal.pone.0021949

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