mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets

Protein kinase B (PKB, Akt) is a Ser/Thr kinase involved in the regulation of cell survival, proliferation, and metabolism and is activated by dual phosphorylation on Thr(308) in the activation loop and Ser(473) in the hydrophobic motif. It plays a contributory role to platelet function, although li...

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Detalles Bibliográficos
Autores principales: Moore, Samantha F., Hunter, Roger W., Hers, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137030/
https://www.ncbi.nlm.nih.gov/pubmed/21592956
http://dx.doi.org/10.1074/jbc.M110.202341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137030/
https://www.ncbi.nlm.nih.gov/pubmed/21592956
http://dx.doi.org/10.1074/jbc.M110.202341

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