Impaired Infectivity of Ritonavir-resistant HIV Is Rescued by Heat Shock Protein 90AB1

Certain ritonavir resistance mutations impair HIV infectivity through incomplete Gag processing by the mutant viral protease. Analysis of the mutant virus phenotype indicates that accumulation of capsid-spacer peptide 1 precursor protein in virus particles impairs HIV infectivity and that the protea...

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Detalles Bibliográficos
Autores principales: Joshi, Pheroze, Stoddart, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137033/
https://www.ncbi.nlm.nih.gov/pubmed/21602280
http://dx.doi.org/10.1074/jbc.M111.248021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137033/
https://www.ncbi.nlm.nih.gov/pubmed/21602280
http://dx.doi.org/10.1074/jbc.M111.248021

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