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Repeated ovarian stimulation with corifollitropin alfa in patients in a GnRH antagonist protocol: no concern for immunogenicity

BACKGROUND: One injection of corifollitropin alfa replaces the first seven daily FSH injections in controlled ovarian stimulation (COS) cycles. Repeated treatment with therapeutic proteins may cause immune responses or hypersensitivity reactions. We assessed the immunogenicity and safety of corifoll...

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Detalles Bibliográficos
Autores principales: Norman, Robert J., Zegers-Hochschild, Fernando, Salle, Bruno S., Elbers, Jolanda, Heijnen, Esther, Marintcheva-Petrova, Maya, Mannaerts, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137390/
https://www.ncbi.nlm.nih.gov/pubmed/21622693
http://dx.doi.org/10.1093/humrep/der163