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Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

BACKGROUND: Carriers of germline mutations in DNA mismatch repair (MMR) genes have a high risk of colorectal cancer (CRC), but the modifiers of this risk are not well established. We estimated an association between body mass index (BMI) in early adulthood and subsequent risk of CRC for carriers and...

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Detalles Bibliográficos
Autores principales: Win, A K, Dowty, J G, English, D R, Campbell, P T, Young, J P, Winship, I, Macrae, F A, Lipton, L, Parry, S, Young, G P, Buchanan, D D, Martínez, M E, Jacobs, E T, Ahnen, D J, Haile, R W, Casey, G, Baron, J A, Lindor, N M, Thibodeau, S N, Newcomb, P A, Potter, J D, Le Marchand, L, Gallinger, S, Hopper, J L, Jenkins, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137400/
https://www.ncbi.nlm.nih.gov/pubmed/21559014
http://dx.doi.org/10.1038/bjc.2011.172