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PEA3/ETV4-related transcription factors coupled with active ERK signalling are associated with poor prognosis in gastric adenocarcinoma

BACKGROUND: Transcription factors often play important roles in tumourigenesis. Members of the PEA3 subfamily of ETS-domain transcription factors fulfil such a role and have been associated with tumour metastasis in several different cancers. Moreover, the activity of the PEA3 subfamily transcriptio...

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Detalles Bibliográficos
Autores principales: Keld, R, Guo, B, Downey, P, Cummins, R, Gulmann, C, Ang, Y S, Sharrocks, A D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137405/
https://www.ncbi.nlm.nih.gov/pubmed/21673681
http://dx.doi.org/10.1038/bjc.2011.187