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Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro
BACKGROUND: Hepatitis B virus X protein (HBx) is involved in the initiation and progression of hepatocellular carcinoma (HCC) by regulating the host protein-coding genes. In this study, we showed that HBx altered the expression of microRNAs (miRNAs) to promote proliferation and transformation in mal...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137408/ https://www.ncbi.nlm.nih.gov/pubmed/21629246 http://dx.doi.org/10.1038/bjc.2011.190 |