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Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro

BACKGROUND: Hepatitis B virus X protein (HBx) is involved in the initiation and progression of hepatocellular carcinoma (HCC) by regulating the host protein-coding genes. In this study, we showed that HBx altered the expression of microRNAs (miRNAs) to promote proliferation and transformation in mal...

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Detalles Bibliográficos
Autores principales:	Wu, G, Yu, F, Xiao, Z, Xu, K, Xu, J, Tang, W, Wang, J, Song, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137408/ https://www.ncbi.nlm.nih.gov/pubmed/21629246 http://dx.doi.org/10.1038/bjc.2011.190

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