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DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6

BACKGROUND: There is limited evidence that imaging biomarkers can predict subsequent response to therapy. Such prognostic and/or predictive biomarkers would facilitate development of personalised medicine. We hypothesised that pre-treatment measurement of the heterogeneity of tumour vascular enhance...

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Detalles Bibliográficos
Autores principales: O'Connor, J P B, Rose, C J, Jackson, A, Watson, Y, Cheung, S, Maders, F, Whitcher, B J, Roberts, C, Buonaccorsi, G A, Thompson, G, Clamp, A R, Jayson, G C, Parker, G J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137409/
https://www.ncbi.nlm.nih.gov/pubmed/21673686
http://dx.doi.org/10.1038/bjc.2011.191