Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

It is widely believed that the alveolar epithelium is unresponsive to LPS, in the absence of serum, due to low expression of TLR4 and CD14. Furthermore, the responsiveness of the epithelium to TLR-2 ligands is also poorly understood. We hypothesised that human alveolar type I (ATI) and type II (ATII...

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Detalles Bibliográficos
Autores principales: Thorley, Andrew J., Grandolfo, Davide, Lim, Eric, Goldstraw, Peter, Young, Alan, Tetley, Teresa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137597/
https://www.ncbi.nlm.nih.gov/pubmed/21789185
http://dx.doi.org/10.1371/journal.pone.0021827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137597/
https://www.ncbi.nlm.nih.gov/pubmed/21789185
http://dx.doi.org/10.1371/journal.pone.0021827

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