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Using an Uncertainty-Coding Matrix in Bayesian Regression Models for Haplotype-Specific Risk Detection in Family Association Studies

Haplotype association studies based on family genotype data can provide more biological information than single marker association studies. Difficulties arise, however, in the inference of haplotype phase determination and in haplotype transmission/non-transmission status. Incorporation of the uncer...

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Detalles Bibliográficos
Autores principales: Huang, Yung-Hsiang, Lee, Mei-Hsien, Chen, Wei J., Hsiao, Chuhsing Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137600/
https://www.ncbi.nlm.nih.gov/pubmed/21789192
http://dx.doi.org/10.1371/journal.pone.0021890