Cargando…

Generation of Germline-Competent Rat Induced Pluripotent Stem Cells

BACKGROUND: Recent progress in rat pluripotent stem cell technology has been remarkable. Particularly salient is the demonstration that embryonic stem cells (ESCs) in the rat (rESCs) can contribute to germline transmission, permitting generation of gene-modified rats as is now done using mouse ESCs...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamanaka, Sanae, Yamaguchi, Tomoyuki, Kobayashi, Toshihiro, Kato-Itoh, Megumi, Yamazaki, Satoshi, Sato, Hideyuki, Umino, Ayumi, Wakiyama, Yukiko, Arai, Mami, Sanbo, Makoto, Hirabayashi, Masumi, Nakauchi, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137610/
https://www.ncbi.nlm.nih.gov/pubmed/21789202
http://dx.doi.org/10.1371/journal.pone.0022008