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CBP/p300 and SIRT1 Are Involved in Transcriptional Regulation of S-Phase Specific Histone Genes

BACKGROUND: Histones constitute a type of essential nuclear proteins important for chromatin structure and functions. The expression of major histones is strictly confined to the S phase of a cell cycle and tightly coupled to DNA replication. METHODOLOGY/PRINCIPAL FINDINGS: With RT-qPCR and ChIP ass...

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Detalles Bibliográficos
Autores principales: He, Hongpeng, Yu, Fa-Xing, Sun, Chi, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137613/
https://www.ncbi.nlm.nih.gov/pubmed/21789216
http://dx.doi.org/10.1371/journal.pone.0022088