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Mechanisms of Allergen-Antibody Interaction of Cockroach Allergen Bla g 2 with Monoclonal Antibodies That Inhibit IgE Antibody Binding

BACKGROUND: Cockroach allergy is strongly associated with asthma, and involves the production of IgE antibodies against inhaled allergens. Reports of conformational epitopes on inhaled allergens are limited. The conformational epitopes for two specific monoclonal antibodies (mAb) that interfere with...

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Detalles Bibliográficos
Autores principales: Glesner, Jill, Wünschmann, Sabina, Li, Mi, Gustchina, Alla, Wlodawer, Alexander, Himly, Martin, Chapman, Martin D., Pomés, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137622/
https://www.ncbi.nlm.nih.gov/pubmed/21789239
http://dx.doi.org/10.1371/journal.pone.0022223