Accelerating Haplotype-Based Genome-Wide Association Study Using Perfect Phylogeny and Phase-Known Reference Data

The genome-wide association study (GWAS) has become a routine approach for mapping disease risk loci with the advent of large-scale genotyping technologies. Multi-allelic haplotype markers can provide superior power compared with single-SNP markers in mapping disease loci. However, the application o...

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Detalles Bibliográficos
Autores principales: He, Yungang, Li, Cong, Amos, Christopher I., Xiong, Momiao, Ling, Hua, Jin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137625/
https://www.ncbi.nlm.nih.gov/pubmed/21789217
http://dx.doi.org/10.1371/journal.pone.0022097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137625/
https://www.ncbi.nlm.nih.gov/pubmed/21789217
http://dx.doi.org/10.1371/journal.pone.0022097

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