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Accelerating Haplotype-Based Genome-Wide Association Study Using Perfect Phylogeny and Phase-Known Reference Data
The genome-wide association study (GWAS) has become a routine approach for mapping disease risk loci with the advent of large-scale genotyping technologies. Multi-allelic haplotype markers can provide superior power compared with single-SNP markers in mapping disease loci. However, the application o...
Autores principales: | He, Yungang, Li, Cong, Amos, Christopher I., Xiong, Momiao, Ling, Hua, Jin, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137625/ https://www.ncbi.nlm.nih.gov/pubmed/21789217 http://dx.doi.org/10.1371/journal.pone.0022097 |
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