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Functional Diversity of Human Basic Helix-Loop-Helix Transcription Factor TCF4 Isoforms Generated by Alternative 5′ Exon Usage and Splicing

BACKGROUND: Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While involved in the development and functioning of many different cell types, recent studies point to important roles for TCF4...

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Detalles Bibliográficos
Autores principales: Sepp, Mari, Kannike, Kaja, Eesmaa, Ave, Urb, Mari, Timmusk, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137626/
https://www.ncbi.nlm.nih.gov/pubmed/21789225
http://dx.doi.org/10.1371/journal.pone.0022138