Cargando…
Functional Diversity of Human Basic Helix-Loop-Helix Transcription Factor TCF4 Isoforms Generated by Alternative 5′ Exon Usage and Splicing
BACKGROUND: Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous class A basic helix-loop-helix protein that binds to E-box DNA sequences (CANNTG). While involved in the development and functioning of many different cell types, recent studies point to important roles for TCF4...
Autores principales: | Sepp, Mari, Kannike, Kaja, Eesmaa, Ave, Urb, Mari, Timmusk, Tõnis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137626/ https://www.ncbi.nlm.nih.gov/pubmed/21789225 http://dx.doi.org/10.1371/journal.pone.0022138 |
Ejemplares similares
-
Isoform-Specific Reduction of the Basic Helix-Loop-Helix Transcription Factor TCF4 Levels in Huntington’s Disease
por: Nurm, Kaja, et al.
Publicado: (2021) -
Forkhead Transcription Factor FOXO3a Levels Are Increased in Huntington Disease Because of Overactivated Positive Autofeedback Loop
por: Kannike, Kaja, et al.
Publicado: (2014) -
An overview of the basic helix-loop-helix proteins
por: Jones, Susan
Publicado: (2004) -
The Evolution of the Neural Basic Helix-Loop-Helix Proteins
por: Vervoort, Michel, et al.
Publicado: (2002) -
Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless
por: Tamberg, Laura, et al.
Publicado: (2015)