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Activation of Protein Kinase C Delta following Cerebral Ischemia Leads to Release of Cytochrome C from the Mitochondria via Bad Pathway

BACKGROUND: The release of cytochrome c from the mitochondria following cerebral ischemia is a key event leading to cell death. The goal of the present study was to determine the mechanisms involved in post-ischemic activation of protein kinase c delta (δPKC) that lead to cytochrome c release. METHO...

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Detalles Bibliográficos
Autores principales: Dave, Kunjan R., Bhattacharya, Sanjoy K., Saul, Isabel, DeFazio, R. Anthony, Dezfulian, Cameron, Lin, Hung Wen, Raval, Ami P., Perez-Pinzon, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137627/
https://www.ncbi.nlm.nih.gov/pubmed/21789211
http://dx.doi.org/10.1371/journal.pone.0022057