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Activation of Protein Kinase C Delta following Cerebral Ischemia Leads to Release of Cytochrome C from the Mitochondria via Bad Pathway
BACKGROUND: The release of cytochrome c from the mitochondria following cerebral ischemia is a key event leading to cell death. The goal of the present study was to determine the mechanisms involved in post-ischemic activation of protein kinase c delta (δPKC) that lead to cytochrome c release. METHO...
Autores principales: | Dave, Kunjan R., Bhattacharya, Sanjoy K., Saul, Isabel, DeFazio, R. Anthony, Dezfulian, Cameron, Lin, Hung Wen, Raval, Ami P., Perez-Pinzon, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137627/ https://www.ncbi.nlm.nih.gov/pubmed/21789211 http://dx.doi.org/10.1371/journal.pone.0022057 |
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