An Integrated Bioinformatics Approach Identifies Elevated Cyclin E2 Expression and E2F Activity as Distinct Features of Tamoxifen Resistant Breast Tumors

Approximately half of estrogen receptor (ER) positive breast tumors will fail to respond to endocrine therapy. Here we used an integrative bioinformatics approach to analyze three gene expression profiling data sets from breast tumors in an attempt to uncover underlying mechanisms contributing to th...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Zhao, Shuangping, Frasor, Jonna M., Dai, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137633/
https://www.ncbi.nlm.nih.gov/pubmed/21789246
http://dx.doi.org/10.1371/journal.pone.0022274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137633/
https://www.ncbi.nlm.nih.gov/pubmed/21789246
http://dx.doi.org/10.1371/journal.pone.0022274

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