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Nuclear Transport Signals Control Cellular Localization and Function of Androgen Receptor Cofactor p44/WDR77

The androgen receptor (AR) cofactor p44/WDR77, which regulates expression of a set of androgen target genes, is required for differentiation of prostate epithelium. Aberrant localization of p44/WDR77 in the cytoplasm is associated with prostate tumorigenesis. Here, we describe studies that used the...

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Detalles Bibliográficos
Autores principales: Gu, Zhongping, Zhou, Liran, Gao, Shen, Wang, Zhengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137635/
https://www.ncbi.nlm.nih.gov/pubmed/21789256
http://dx.doi.org/10.1371/journal.pone.0022395