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Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter

The maintenance of cell shape in Caulobacter crescentus requires the essential gene mreB, which encodes a member of the actin superfamily and the target of the antibiotic, A22. We isolated 35 unique A22-resistant Caulobacter strains with single amino acid substitutions near the nucleotide binding si...

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Detalles Bibliográficos
Autores principales: Dye, Natalie A, Pincus, Zachary, Fisher, Isabelle C, Shapiro, Lucy, Theriot, Julie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137890/
https://www.ncbi.nlm.nih.gov/pubmed/21564339
http://dx.doi.org/10.1111/j.1365-2958.2011.07698.x