Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs

Conformationally preorganized peptide nucleic acids (PNAs) have been synthesized through backbone modifications at the γ-position, where R = alanine, valine, isoleucine, and phenylalanine side chains. The effects of these side-chains on the conformations and hybridization properties of PNAs were det...

Descripción completa

Detalles Bibliográficos
Autores principales: Crawford, Matthew J., Rapireddy, Srinivas, Bahal, Raman, Sacui, Iulia, Ly, Danith H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138043/
https://www.ncbi.nlm.nih.gov/pubmed/21776375
http://dx.doi.org/10.4061/2011/652702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138043/
https://www.ncbi.nlm.nih.gov/pubmed/21776375
http://dx.doi.org/10.4061/2011/652702

Ejemplares similares