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Delineating an Epigenetic Continuum for Initiation, Transformation and Progression to Breast Cancer
Aberrant methylation of promoter CpG islands is a hallmark of human cancers and is an early event in carcinogenesis. We examined whether promoter hypermethylation contributes to the pathogenesis of benign breast lesions along a progression continuum to invasive breast cancer. The exploratory study c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138135/ https://www.ncbi.nlm.nih.gov/pubmed/21776373 http://dx.doi.org/10.3390/cancers3021580 |