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Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development

SUR-8, a conserved leucine-rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis elegans. Biochemical studies indicated that SUR-8 interacts with Ras and Raf, leading to the elevated ERK activity. However, the physiological role of SUR-8 during mammalian...

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Detalles Bibliográficos
Autores principales: Yi, Jing, Chen, Muyun, Wu, Xiaohui, Yang, Xiao, Xu, Tian, Zhuang, Yuan, Han, Min, Xu, Rener
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Liss, Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138404/
https://www.ncbi.nlm.nih.gov/pubmed/20549726
http://dx.doi.org/10.1002/dvdy.22343