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Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development
SUR-8, a conserved leucine-rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis elegans. Biochemical studies indicated that SUR-8 interacts with Ras and Raf, leading to the elevated ERK activity. However, the physiological role of SUR-8 during mammalian...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wiley-Liss, Inc.
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138404/ https://www.ncbi.nlm.nih.gov/pubmed/20549726 http://dx.doi.org/10.1002/dvdy.22343 |