A comparison of a new multinomial stopping rule with stopping rules of fleming and gehan in single arm phase II cancer clinical trials

BACKGROUND: Response rate (RR) alone may be insensitive to drug activity in phase II trials. Early progressive disease (EPD) could improve sensitivity as well as increase stage I stopping rates. This study compares the previously developed dual endpoint stopping rule (DESR), which incorporates both...

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Detalles Bibliográficos
Autores principales: Goffin, John R, Pond, Greg R, Tu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138426/
https://www.ncbi.nlm.nih.gov/pubmed/21693051
http://dx.doi.org/10.1186/1471-2288-11-95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138426/
https://www.ncbi.nlm.nih.gov/pubmed/21693051
http://dx.doi.org/10.1186/1471-2288-11-95

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