Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif

BACKGROUND: The interactions between PDZ (PSD-95, Dlg, ZO-1) domains and PDZ-binding motifs play central roles in signal transductions within cells. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively when the motifs are located at the carboxyl (C-) terminal ends of their binding...

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Detalles Bibliográficos
Autores principales: Chimura, Takahiko, Launey, Thomas, Ito, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138430/
https://www.ncbi.nlm.nih.gov/pubmed/21649932
http://dx.doi.org/10.1186/1471-2164-12-300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138430/
https://www.ncbi.nlm.nih.gov/pubmed/21649932
http://dx.doi.org/10.1186/1471-2164-12-300

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