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Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif
BACKGROUND: The interactions between PDZ (PSD-95, Dlg, ZO-1) domains and PDZ-binding motifs play central roles in signal transductions within cells. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively when the motifs are located at the carboxyl (C-) terminal ends of their binding...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138430/ https://www.ncbi.nlm.nih.gov/pubmed/21649932 http://dx.doi.org/10.1186/1471-2164-12-300 |