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Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion
Host cyclophilin (cyp) inhibitors, such as NIM811, efficiently inhibit replication of hepatitis C virus (HCV) and have shown significant promise in recent clinical trials for the treatment of chronic HCV. It is therefore important to fully understand the mechanism of action of these therapeutic agen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138436/ https://www.ncbi.nlm.nih.gov/pubmed/21711559 http://dx.doi.org/10.1186/1743-422X-8-329 |