Effect of different UCOE-promoter combinations in creation of engineered cell lines for the production of Factor VIII

BACKGROUND: The most common approach used in generating cell lines for the production of therapetic proteins relies on gene amplification induced by a drug resistance gene e. g., DHFR and glutamine synthetase. Practically, this results in screening large number of clones for the one that expresses h...

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Detalles Bibliográficos
Autores principales: Nair, Ayyappan R, Jinger, Xie, Hermiston, Terry W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138458/
https://www.ncbi.nlm.nih.gov/pubmed/21663669
http://dx.doi.org/10.1186/1756-0500-4-178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138458/
https://www.ncbi.nlm.nih.gov/pubmed/21663669
http://dx.doi.org/10.1186/1756-0500-4-178

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