Cargando…
Effect of different UCOE-promoter combinations in creation of engineered cell lines for the production of Factor VIII
BACKGROUND: The most common approach used in generating cell lines for the production of therapetic proteins relies on gene amplification induced by a drug resistance gene e. g., DHFR and glutamine synthetase. Practically, this results in screening large number of clones for the one that expresses h...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138458/ https://www.ncbi.nlm.nih.gov/pubmed/21663669 http://dx.doi.org/10.1186/1756-0500-4-178 |