Exploiting Mitochondrial Dysfunction for Effective Elimination of Imatinib-Resistant Leukemic Cells

Challenges today concern chronic myeloid leukemia (CML) patients resistant to imatinib. There is growing evidence that imatinib-resistant leukemic cells present abnormal glucose metabolism but the impact on mitochondria has been neglected. Our work aimed to better understand and exploit the metaboli...

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Detalles Bibliográficos
Autores principales: Kluza, Jérome, Jendoubi, Manel, Ballot, Caroline, Dammak, Abir, Jonneaux, Aurélie, Idziorek, Thierry, Joha, Sami, Dauphin, Véronique, Malet-Martino, Myriam, Balayssac, Stéphane, Maboudou, Patrice, Briand, Gilbert, Formstecher, Pierre, Quesnel, Bruno, Marchetti, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138741/
https://www.ncbi.nlm.nih.gov/pubmed/21789194
http://dx.doi.org/10.1371/journal.pone.0021924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138741/
https://www.ncbi.nlm.nih.gov/pubmed/21789194
http://dx.doi.org/10.1371/journal.pone.0021924

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