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A host-restricted viral vector for antigen-specific immunization against Lyme disease pathogen
Newcastle disease virus (NDV) is an avian virus that is attenuated in primates and is a potential vaccine vector for human use. We evaluated NDV as a vector for expressing selected antigens of the Lyme disease pathogen Borrelia burgdorferi. A series of recombinant NDVs were generated that expressed...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd. Published by Elsevier Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138909/ https://www.ncbi.nlm.nih.gov/pubmed/21600949 http://dx.doi.org/10.1016/j.vaccine.2011.05.010 |