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A host-restricted viral vector for antigen-specific immunization against Lyme disease pathogen

Newcastle disease virus (NDV) is an avian virus that is attenuated in primates and is a potential vaccine vector for human use. We evaluated NDV as a vector for expressing selected antigens of the Lyme disease pathogen Borrelia burgdorferi. A series of recombinant NDVs were generated that expressed...

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Detalles Bibliográficos
Autores principales: Xiao, Sa, Kumar, Manish, Yang, Xiuli, Akkoyunlu, Mustafa, Collins, Peter L., Samal, Siba K., Pal, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. Published by Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138909/
https://www.ncbi.nlm.nih.gov/pubmed/21600949
http://dx.doi.org/10.1016/j.vaccine.2011.05.010