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Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation

Tau is primarily a neuronal microtubule-associated protein that has functions related to the stabilisation of microtubules. Phosphorylation of tau is an important dynamic and regulatory element involved in the binding of tau to tubulin. Thus, highly phosphorylated tau is more likely to be present in...

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Detalles Bibliográficos
Autores principales: Hanger, Diane P., Noble, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139124/
https://www.ncbi.nlm.nih.gov/pubmed/21776376
http://dx.doi.org/10.4061/2011/352805