Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis

Background. Alzheimer's disease (AD) is a devastating neurological disorder and the main cause of dementia in the elderly population worldwide. Adult neurogenesis appears to be upregulated very early in AD pathogenesis in response to some specific aggregates of beta-amyloid (Aβ) peptides, exhau...

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Detalles Bibliográficos
Autores principales: Modarresi, Farzaneh, Faghihi, Mohammad Ali, Patel, Nikunj S., Sahagan, Barbara G., Wahlestedt, Claes, Lopez-Toledano, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139208/
https://www.ncbi.nlm.nih.gov/pubmed/21785702
http://dx.doi.org/10.4061/2011/929042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139208/
https://www.ncbi.nlm.nih.gov/pubmed/21785702
http://dx.doi.org/10.4061/2011/929042

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