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Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis
Background. Alzheimer's disease (AD) is a devastating neurological disorder and the main cause of dementia in the elderly population worldwide. Adult neurogenesis appears to be upregulated very early in AD pathogenesis in response to some specific aggregates of beta-amyloid (Aβ) peptides, exhau...
Autores principales: | Modarresi, Farzaneh, Faghihi, Mohammad Ali, Patel, Nikunj S., Sahagan, Barbara G., Wahlestedt, Claes, Lopez-Toledano, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139208/ https://www.ncbi.nlm.nih.gov/pubmed/21785702 http://dx.doi.org/10.4061/2011/929042 |
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