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GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease characterized by late diagnosis and treatment resistance. Recurrent genetic alterations in defined genes in association with perturbations of developmental cell signaling pathways have been associated with PDAC development and progre...

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Detalles Bibliográficos
Autores principales: Zhong, Yi, Wang, Zheng, Fu, Baojin, Pan, Fan, Yachida, Shinichi, Dhara, Mousumi, Albesiano, Emilia, Li, Li, Naito, Yoshiki, Vilardell, Felip, Cummings, Christopher, Martinelli, Paola, Li, Ang, Yonescu, Raluca, Ma, Qingyong, Griffin, Constance A., Real, Francisco X., Iacobuzio-Donahue, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139620/
https://www.ncbi.nlm.nih.gov/pubmed/21811562
http://dx.doi.org/10.1371/journal.pone.0022129